Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 3/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 12/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.33 |
| ▸ | CRACR2A | Q9BSW2 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5312642 | 0.90 | SCD (0.36) | SCDP2RX7EGLN1CYP2C9MAPK11 | |
| SCHEMBL5313381 | 0.86 | SCD (0.41) | SCDP2RX7EGLN1CRACR2ACYP2C9 | |
| SCHEMBL5312064 | 0.83 | SCD (0.43) | SCDP2RX7CRACR2A | |
| SCHEMBL5310028 | 0.83 | EGLN1 (0.37) | SCDP2RX7EGLN1CYP2C9MAPK11 | |
| SCHEMBL5309303 | 0.83 | SCD (0.44) | SCDP2RX7EGLN1CRACR2ACYP2C9 | |
| SCHEMBL5309204 | 0.80 | SCD (0.37) | SCDP2RX7EGLN1CYP2C9MAPK11 | |
| SCHEMBL5310358 | 0.80 | SMN1; SMN2 (0.44) | CRACR2A | |
| SCHEMBL5312062 | 0.79 | SCD (0.49) | SCD | |
| SCHEMBL5309835 | 0.78 | SCD (0.51) | SCDEGLN1 | |
| SCHEMBL5309661 | 0.77 | SCD (0.53) | SCDEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046867-A2 | PIPERIDINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2007-04-26 | — | — | WO | disclosed |