Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2645015 | 0.76 | ATM (0.37) | ATMMEN1KMT2A | |
| SCHEMBL16935647 | 0.75 | ATM (0.35) | ATM | |
| SCHEMBL22657793 | 0.75 | MAPK1 (0.32) | KMT2A | |
| SCHEMBL2644912 | 0.75 | L3MBTL1 (0.38) | ATMMEN1KMT2A | |
| SCHEMBL9192901 | 0.74 | LMNA (0.35) | MEN1KMT2A | |
| SCHEMBL2646658 | 0.73 | L3MBTL1 (0.46) | ATMMEN1KMT2A | |
| SCHEMBL22657919 | 0.73 | MAPK1 (0.31) | — | |
| SCHEMBL7837036 | 0.72 | L3MBTL1 (0.53) | ATMMEN1KMT2A | |
| SCHEMBL2184936 | 0.71 | ATM (0.50) | ATMMEN1KMT2A | |
| SCHEMBL2645771 | 0.70 | ALDH1A1 (0.36) | ATMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592426-B1 | 2-CYANOPYRROLOPYRIMIDINES AND PHARMACEUTICAL USES THEREOF | NOVARTIS AG (CH) | 2007-12-19 | — | — | EP | claimed |