Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 4/20 | 0.41 |
| ▸ | DYRK2 | Q92630 | 7/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | CDK6 | Q00534 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5312932 | 0.93 | KDR (0.42) | KDRFAAHDYRK2PRKAA2CDK4 | |
| SCHEMBL5310039 | 0.91 | FAAH (0.39) | FAAHDYRK2PRKAA2CDK4CDK6 | |
| SCHEMBL5314116 | 0.89 | DYRK2 (0.39) | DYRK2CDK4CCND1CDK6 | |
| SCHEMBL14531377 | 0.89 | DYRK2 (0.40) | DYRK2CDK4CCND1CDK6 | |
| SCHEMBL5316079 | 0.89 | CDK4 (0.40) | DYRK2CDK4CCND1 | |
| SCHEMBL5315529 | 0.88 | DYRK2 (0.40) | KDRDYRK2CDK4CCND1CDK6 | |
| SCHEMBL5313455 | 0.87 | DYRK2 (0.47) | DYRK2CDK4CCND1CDK6 | |
| SCHEMBL14531378 | 0.84 | MELK (0.39) | DYRK2CDK4CCND1 | |
| SCHEMBL5312795 | 0.84 | KDR (0.42) | KDRFAAHDYRK2PRKAA2CDK4 | |
| SCHEMBL5335400 | 0.83 | KDR (0.53) | KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | claimed |
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |