Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK2 | Q92630 | 11/20 | 0.47 |
| ▸ | CDK6 | Q00534 | 8/20 | 0.41 |
| ▸ | CCND1 | P24385 | 4/20 | 0.41 |
| ▸ | CDK4 | P11802 | 3/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.40 |
| ▸ | CCND3 | P30281 | 2/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | LYN | P07948 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14531377 | 0.91 | DYRK2 (0.40) | DYRK2CDK6CCND1CDK4CCNA2 | |
| SCHEMBL5315529 | 0.89 | DYRK2 (0.40) | DYRK2CDK6CCND1CDK4CCNA2 | |
| SCHEMBL5314116 | 0.89 | DYRK2 (0.39) | DYRK2CDK6CCND1CDK4CCNA2 | |
| SCHEMBL5312932 | 0.88 | KDR (0.42) | DYRK2CDK6CCND1CDK4 | |
| SCHEMBL5316079 | 0.87 | CDK4 (0.40) | DYRK2CCND1CDK4 | |
| SCHEMBL5312799 | 0.87 | KDR (0.41) | DYRK2CDK6CCND1CDK4 | |
| SCHEMBL5310039 | 0.87 | FAAH (0.39) | DYRK2CDK6CDK4CDK2 | |
| SCHEMBL14531378 | 0.86 | MELK (0.39) | DYRK2CCND1CDK4 | |
| SCHEMBL5311790 | 0.81 | IDO1 (0.40) | DYRK2CCND1CDK4 | |
| SCHEMBL14531379 | 0.80 | KDR (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |