Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | TDO2 | P48775 | 2/20 | 0.39 |
| ▸ | DYRK2 | Q92630 | 6/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.36 |
| ▸ | TCF7L2 | Q9NQB0 | 2/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.35 |
| ▸ | CCR3 | P51677 | 2/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5315529 | 0.91 | DYRK2 (0.40) | CDK4CCND1DYRK2 | |
| SCHEMBL5312799 | 0.89 | KDR (0.41) | CDK4CCND1DYRK2 | |
| SCHEMBL5312932 | 0.88 | KDR (0.42) | CDK4CCND1DYRK2LTA4H | |
| SCHEMBL14531377 | 0.87 | DYRK2 (0.40) | CDK4CCND1DYRK2 | |
| SCHEMBL5311790 | 0.87 | IDO1 (0.40) | CDK4CCND1IDO1TDO2DYRK2 | |
| SCHEMBL5310039 | 0.87 | FAAH (0.39) | CDK4DYRK2 | |
| SCHEMBL14531378 | 0.87 | MELK (0.39) | CDK4CCND1DYRK2 | |
| SCHEMBL5313455 | 0.87 | DYRK2 (0.47) | CDK4CCND1DYRK2 | |
| SCHEMBL5314116 | 0.86 | DYRK2 (0.39) | CDK4CCND1DYRK2 | |
| SCHEMBL5311458 | 0.83 | IDO1 (0.43) | CDK4CCND1IDO1TDO2DYRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | claimed |
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |