Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.53 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.53 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5315547 | 0.99 | ALDH1A1 (0.62) | ALDH1A1TSHRHSD17B10KDM4ECYP3A4 | |
| SCHEMBL5308328 | 0.84 | HDAC3 (0.61) | ALDH1A1KDM4EKMT2ACHRNB2CHRNB4 | |
| SCHEMBL5308137 | 0.83 | MEN1 (0.60) | ALDH1A1KDM4EKMT2ACHRNB2CHRNB4 | |
| SCHEMBL5461588 | 0.76 | HDAC1 (0.58) | ALDH1A1KMT2APOLBMAPTMEN1 | |
| SCHEMBL20964516 | 0.75 | ALDH1A1 (0.68) | ALDH1A1TSHRHSD17B10KDM4ECYP3A4 | |
| SCHEMBL5334215 | 0.74 | SLC27A1 (0.58) | ALDH1A1KMT2APOLBSMN1; SMN2MAPT | |
| SCHEMBL5314683 | 0.73 | MEN1 (0.62) | ALDH1A1KDM4EKMT2ACHRNB2CHRNB4 | |
| SCHEMBL5605575 | 0.72 | MEN1 (0.63) | ALDH1A1TSHRCYP3A4CYP2D6CYP2C19 | |
| SCHEMBL5421106 | 0.72 | KCNA5 (0.52) | KMT2ALMNASMN1; SMN2 | |
| SCHEMBL5333039 | 0.72 | KDM4E (0.57) | ALDH1A1HSD17B10KDM4EKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070088043-A1 | Novel HDAC inhibitors | ORCHID RESEARCH LABORATORIES LIMITED. (IN) | 2007-04-19 | — | — | US | claimed |
| WO-2007045962-A2 | NOVEL HDAC INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-04-26 | — | — | WO | disclosed |
| US-20070088043-A1 | Novel HDAC inhibitors | ORCHID RESEARCH LABORATORIES LIMITED. (IN) | 2007-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070088043-A1 | Novel HDAC inhibitors | HDAC1, HDAC11, HDAC5 | ALDH1A1 681/4885TSHR 3776/4885HSD17B10 502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.