Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.53 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.53 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.53 |
| ▸ | ME2 | P23368 | 1/20 | 0.53 |
| ▸ | ME1 | P48163 | 1/20 | 0.53 |
| ▸ | ME3 | Q16798 | 1/20 | 0.53 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.52 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14520828 | 0.90 | HDAC1 (0.62) | MEN1KMT2AALDH1A1NPC1LMNA | |
| SCHEMBL5308328 | 0.89 | HDAC3 (0.61) | MEN1KMT2AALDH1A1NPC1LMNA | |
| SCHEMBL5308137 | 0.88 | MEN1 (0.60) | MEN1KMT2AALDH1A1NPC1LMNA | |
| SCHEMBL14520805 | 0.85 | HDAC3 (0.65) | MEN1KMT2AALDH1A1NPC1LMNA | |
| SCHEMBL14520829 | 0.85 | ALDH1A1 (0.59) | MEN1KMT2AALDH1A1NPC1LMNA | |
| SCHEMBL14520802 | 0.83 | HDAC3 (0.62) | MEN1KMT2AALDH1A1NPC1LMNA | |
| SCHEMBL6893687 | 0.82 | ALDH1A1 (0.79) | MEN1KMT2AALDH1A1NPC1LMNA | |
| SCHEMBL5605575 | 0.81 | MEN1 (0.63) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL14192211 | 0.80 | ALDH1A1 (0.72) | MEN1KMT2AALDH1A1NPC1LMNA | |
| SCHEMBL5333226 | 0.79 | SLC27A1 (0.59) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007045962-A2 | NOVEL HDAC INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-04-26 | — | — | WO | disclosed |
| US-20070088043-A1 | Novel HDAC inhibitors | ORCHID RESEARCH LABORATORIES LIMITED. (IN) | 2007-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070088043-A1 | Novel HDAC inhibitors | HDAC1, HDAC11, HDAC5 | MEN1 4128/4885KMT2A 168/4885ALDH1A1 681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.