Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL531305 | 1.00 | GPR139 (0.48) | GPR139ALDH1A1AURKAGPR27KMT2A | |
| SCHEMBL529269 | 0.91 | ALDH1A1 (0.46) | GPR139ALDH1A1AURKAGPR27KMT2A | |
| SCHEMBL529268 | 0.91 | ALDH1A1 (0.46) | GPR139ALDH1A1AURKAGPR27KMT2A | |
| SCHEMBL528620 | 0.89 | ALDH1A1 (0.48) | GPR139ALDH1A1KMT2AKDM4EHTT | |
| SCHEMBL528621 | 0.89 | ALDH1A1 (0.48) | GPR139ALDH1A1KMT2AKDM4EHTT | |
| SCHEMBL531077 | 0.85 | GPR139 (0.40) | GPR139ALDH1A1AURKAGPR27KMT2A | |
| SCHEMBL531078 | 0.85 | GPR139 (0.40) | GPR139ALDH1A1AURKAGPR27KMT2A | |
| SCHEMBL526554 | 0.84 | ALDH1A1 (0.52) | GPR139ALDH1A1KMT2AKDM4EHTT | |
| SCHEMBL527662 | 0.84 | KMT2A (0.45) | GPR139ALDH1A1KMT2AKDM4EHTT | |
| SCHEMBL527661 | 0.84 | KMT2A (0.45) | GPR139ALDH1A1KMT2AKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598493-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012014114-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |