Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5313185 | 1.00 | ALDH1A1 (0.40) | ALDH1A1KDM4ELMNAMAPTL3MBTL1 | |
| SCHEMBL5308888 | 0.94 | ALDH1A1 (0.44) | ALDH1A1KDM4ELMNAMAPTL3MBTL1 | |
| SCHEMBL5308884 | 0.94 | ALDH1A1 (0.44) | ALDH1A1KDM4ELMNAMAPTL3MBTL1 | |
| SCHEMBL5311481 | 0.93 | ALDH1A1 (0.40) | ALDH1A1KDM4ELMNAMAPTL3MBTL1 | |
| SCHEMBL5311478 | 0.93 | ALDH1A1 (0.40) | ALDH1A1KDM4ELMNAMAPTL3MBTL1 | |
| SCHEMBL5311126 | 0.88 | ALDH1A1 (0.42) | ALDH1A1KDM4ELMNAMAPTFAAH | |
| SCHEMBL5311122 | 0.88 | ALDH1A1 (0.42) | ALDH1A1KDM4ELMNAMAPTFAAH | |
| SCHEMBL5314095 | 0.86 | LMNA (0.43) | ALDH1A1KDM4ELMNAMAPTL3MBTL1 | |
| SCHEMBL5314097 | 0.86 | LMNA (0.43) | ALDH1A1KDM4ELMNAMAPTL3MBTL1 | |
| SCHEMBL5308706 | 0.85 | MEN1 (0.37) | ALDH1A1LMNAABCB1ENPP2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044796-A2 | PYRIDAZINONE COMPOUNDS AS CALCILYTICS | NPS PHARMACEUTICALS, INC. (US) | 2007-04-19 | — | — | WO | disclosed |