Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 8/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PPIA | P62937 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5315704 | 0.93 | RAB9A (0.35) | POLBRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL5314164 | 0.90 | GAA (0.38) | GAAPOLBLMNAMAPTL3MBTL1 | |
| SCHEMBL5389734 | 0.88 | TLR7 (0.39) | GAAPOLBLMNAMAPTRAB9A | |
| SCHEMBL4154465 | 0.85 | RORC (0.41) | GAAPOLBRORCLMNAMAPT | |
| SCHEMBL5313896 | 0.85 | TLR7 (0.36) | GAAPOLBLMNAMAPTL3MBTL1 | |
| SCHEMBL5314263 | 0.85 | TLR7 (0.36) | GAAPOLBRORCLMNAMAPT | |
| SCHEMBL5314173 | 0.84 | KDM4E (0.35) | GAARORCLMNARAB9AKDM4E | |
| SCHEMBL5313998 | 0.83 | RAB9A (0.36) | GAAPOLBMAPTL3MBTL1RAB9A | |
| SCHEMBL5314610 | 0.83 | POLB (0.40) | GAAPOLBLMNAMAPTL3MBTL1 | |
| SCHEMBL5311213 | 0.83 | RAB9A (0.35) | GAAPOLBRORCMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007066496-A1 | BENZOYLUREA COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-14 | — | — | WO | disclosed |