Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5314173 | 0.96 | KDM4E (0.35) | TLR7TLR8LMNAGAAKDM4E | |
| SCHEMBL5312106 | 0.93 | TRPA1 (0.35) | TLR7TLR8LMNANPC1MAPT | |
| SCHEMBL5314263 | 0.91 | TLR7 (0.36) | TLR7TLR8LMNAGAAKDM4E | |
| SCHEMBL5313896 | 0.91 | TLR7 (0.36) | TLR7TLR8LMNAGAAKDM4E | |
| SCHEMBL5314164 | 0.90 | GAA (0.38) | TLR7TLR8LMNAGAAMAPT | |
| SCHEMBL5425678 | 0.88 | P2RX7 (0.38) | LMNA | |
| SCHEMBL5313207 | 0.88 | GAA (0.37) | TLR7TLR8LMNAGAAKDM4E | |
| SCHEMBL5315040 | 0.87 | RXFP1 (0.35) | — | |
| SCHEMBL5314713 | 0.86 | TRPA1 (0.34) | NPC1MAPTRAB9APOLB | |
| SCHEMBL5314730 | 0.85 | KMT2A (0.36) | NPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007066496-A1 | BENZOYLUREA COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-14 | — | — | WO | disclosed |