Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.38 |
| ▸ | IL2 | P60568 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5316819 | 0.86 | TLR8 (0.44) | KDM4ETLR7TLR8KMT2A | |
| SCHEMBL5315683 | 0.84 | KMT2A (0.47) | KDM4EHPGDSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL5312166 | 0.83 | CA1 (0.39) | RORCHTTKMT2AALDH1A1 | |
| SCHEMBL5318473 | 0.83 | HTT (0.37) | SMN1; SMN2HTTKMT2AALDH1A1 | |
| SCHEMBL5315021 | 0.83 | HTT (0.37) | KDM4ESMN1; SMN2HTTKMT2AALDH1A1 | |
| SCHEMBL5315879 | 0.83 | HTT (0.34) | SCN9AKDM4EHPGDSMN1; SMN2HTT | |
| SCHEMBL5335591 | 0.83 | HTT (0.34) | SCN9ASMN1; SMN2TRPA1CYP1A2HTT | |
| SCHEMBL5311739 | 0.83 | ALDH1A1 (0.36) | SCN9ASMN1; SMN2TLR7HTTTLR8 | |
| SCHEMBL5314296 | 0.81 | ALDH1A1 (0.35) | SCN9ASMN1; SMN2RORCHTTKMT2A | |
| SCHEMBL5318469 | 0.80 | SMN1; SMN2 (0.36) | HPGDSMN1; SMN2HTTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007066496-A1 | BENZOYLUREA COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-14 | — | — | WO | disclosed |