Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 6/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 2/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5315021 | 0.87 | HTT (0.37) | HTTRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL5335591 | 0.86 | HTT (0.34) | HTTRAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL5318469 | 0.86 | SMN1; SMN2 (0.36) | HTTRAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL5314296 | 0.85 | ALDH1A1 (0.35) | HTTRAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL5316805 | 0.83 | MEN1 (0.34) | HTTPOLBDHODHMEN1KMT2A | |
| SCHEMBL5313867 | 0.83 | MAPT (0.38) | RAB9ANPC1SMN1; SMN2POLBMEN1 | |
| SCHEMBL5313291 | 0.83 | SCN9A (0.44) | HTTSMN1; SMN2KDM4EHPGDSCN9A | |
| SCHEMBL5313356 | 0.80 | KMT2A (0.38) | RAB9ASMN1; SMN2KDM4EPOLBMEN1 | |
| SCHEMBL5315683 | 0.80 | KMT2A (0.47) | RAB9ANPC1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL5314390 | 0.80 | LMNA (0.36) | RAB9ANPC1SMN1; SMN2POLBDHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007066496-A1 | BENZOYLUREA COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-14 | — | — | WO | disclosed |