SCHEMBL5313434

SCHEMBL5313434

CNC(=O)C1(C#N)CCCO1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11286302 0.76
SCHEMBL27454182 0.69 GLS (0.46) CYP3A4SMN1; SMN2
SCHEMBL21779938 0.69 ADORA2A (0.35) CYP3A4SMN1; SMN2
SCHEMBL24770416 0.68 LMNA (0.34) CYP3A4
SCHEMBL12311363 0.68
SCHEMBL20599744 0.67 CYP3A4 (0.32) CYP3A4SMN1; SMN2
SCHEMBL1849141 0.66 NPSR1 (0.36) CYP3A4
SCHEMBL12736731 0.62 THRB (0.37)
SCHEMBL15959260 0.60 MCL1 (0.30)
SCHEMBL23520425 0.60 KDM4E (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007063556-A2 AN IMPROVED AND INDUSTRIAL PROCESS FOR THE PREPARATION OF ALFUZOSIN HYDROCHLORIDE AND ITS NOVEL POLYMORPHS MSN LABORATORIES LIMITED (IN) 2007-06-07 WO disclosed