Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 6/20 | 0.35 |
| ▸ | FDPS | P14324 | 9/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | PNLIP | P16233 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclocoulterone SCHEMBL14542275 | 1.00 | GGPS1 (0.35) | GGPS1FDPSUSP2MEN1KMT2A | |
| SCHEMBL18290368 | 0.69 | FDPS (0.43) | GGPS1FDPSUSP2MEN1KMT2A | |
| Orthosiphonol SCHEMBL29532734 | 0.65 | FDPS (0.42) | GGPS1FDPSUSP2MEN1KMT2A | |
| SCHEMBL29637840 | 0.63 | USP2 (0.50) | GGPS1FDPSUSP2MEN1KMT2A | |
| SCHEMBL14542274 | 0.62 | FDPS (0.43) | GGPS1FDPSUSP2MEN1KMT2A | |
| Taiwaniaquinol A SCHEMBL31237196 | 0.60 | FDPS (0.33) | GGPS1FDPSUSP2MEN1KMT2A | |
| SCHEMBL29713175 | 0.59 | FDPS (0.57) | GGPS1FDPSUSP2MEN1KMT2A | |
| Demethylcryptojaponol SCHEMBL13532270 | 0.55 | FDPS (0.67) | GGPS1FDPSUSP2MEN1KMT2A | |
| Demethylcryptojaponol SCHEMBL16006713 | 0.55 | FDPS (0.67) | GGPS1FDPSUSP2MEN1KMT2A | |
| Demethylcryptojaponol SCHEMBL28596866 | 0.55 | FDPS (0.67) | GGPS1FDPSUSP2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038875-A1 | CCR5 RECEPTOR ANTAGONIST MOLECULES | AVANCE PHARMA INC. (CA) | 2007-04-12 | — | — | WO | disclosed |