Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | RXRB | P28702 | 2/20 | 0.36 |
| ▸ | RXRG | P48443 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL434864 | 0.75 | POLB (0.59) | POLBTDP1TSHRNPC1RAB9A | |
| SCHEMBL6167829 | 0.72 | ALOX15 (0.59) | POLBTDP1TSHRNPC1RAB9A | |
| SCHEMBL22681634 | 0.71 | POLB (0.52) | POLBTDP1TSHRTRPM8ALOX15 | |
| SCHEMBL529695 | 0.71 | MAPT (0.50) | POLBTSHRNPC1RAB9AHSD17B10 | |
| SCHEMBL10071512 | 0.69 | NQO1 (0.54) | POLBTDP1TSHRNPC1ALOX15 | |
| SCHEMBL22682035 | 0.68 | POLB (0.49) | POLBTDP1TSHRTRPM8ALOX15 | |
| SCHEMBL529873 | 0.68 | LMNA (0.48) | POLBTDP1NPC1RAB9AALDH1A1 | |
| SCHEMBL22681623 | 0.68 | POLB (0.43) | POLBTDP1TSHRNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL3894376 | 0.64 | ADRA2A (0.62) | POLBTDP1 | |
| SCHEMBL23222346 | 0.64 | SMN1; SMN2 (0.56) | POLBTSHRNPC1RAB9AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | claimed |