Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.61 |
| ▸ | BCHE | P06276 | 4/20 | 0.61 |
| ▸ | ACHE | P22303 | 4/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3653095 | 0.87 | EPHX2 (0.77) | KMT2AMEN1BCHEACHEEPHX2 | |
| SCHEMBL9367263 | 0.84 | NR1H4 (0.83) | KMT2AMEN1NR1H4EPHX2L3MBTL1 | |
| SCHEMBL14344626 | 0.82 | MEN1 (0.76) | KMT2AMEN1NR1H4L3MBTL1SMN1; SMN2 | |
| SCHEMBL11271316 | 0.81 | KMT2A (0.55) | KMT2AMEN1EPHX2SMN1; SMN2LMNA | |
| SCHEMBL11285414 | 0.80 | NLRP3 (0.74) | KMT2AMEN1NR1H4BCHEACHE | |
| SCHEMBL9370863 | 0.80 | ALDH1A1 (0.88) | KMT2AMEN1EPHX2L3MBTL1SMN1; SMN2 | |
| SCHEMBL4589826 | 0.79 | PTGS1 (0.73) | KMT2AMEN1NR1H4L3MBTL1SMN1; SMN2 | |
| SCHEMBL11277313 | 0.79 | L3MBTL1 (0.52) | KMT2AMEN1EPHX2L3MBTL1SMN1; SMN2 | |
| SCHEMBL5103284 | 0.79 | USP2 (0.84) | KMT2AMEN1EPHX2L3MBTL1SMN1; SMN2 | |
| SCHEMBL28869814 | 0.78 | NR1H4 (0.73) | KMT2AMEN1NR1H4L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327022-A | Heterocyclic alkyl naphthols | STERLING DRUG INC. (US) | 1982-04-27 | — | — | US | disclosed |
| US-4169108-A | 5(OR 6)-[(Substituted-amino)alkyl]-2,3-naphthalenediols | STERLING DRUG INC. (US) | 1979-09-25 | — | — | US | disclosed |