Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.87 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.87 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.58 |
| ▸ | ADH1B | P00325 | 2/20 | 0.57 |
| ▸ | ADH1C | P00326 | 2/20 | 0.57 |
| ▸ | ADH1A | P07327 | 2/20 | 0.57 |
| ▸ | ADH7 | P40394 | 2/20 | 0.57 |
| ▸ | ADH4 | P08319 | 1/20 | 0.57 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.56 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.56 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.56 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.56 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5165020 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL4315670 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL8980568 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL8980623 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL6545006 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL25210211 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL5502786 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL5500928 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL21611676 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL237903 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108779233-A | Hardener composition for epoxy resin based coating compositions, method for the preparation and use thereof | 湛新奥地利有限公司 | 2018-11-09 | — | — | CN | claimed |
| US-11819584-B2 | Nucleic acid decontamination methods | CEPHEID (US) | 2023-11-21 | — | — | US | disclosed |
| WO-2023196679-A1 | 2,3-PYRROLIDINEDIONE CONJUGATES AND METHODS OF USING THEREOF | NORTH CAROLINA STATE UNIVERSITY (US) | 2023-10-12 | — | — | WO | disclosed |
| CN-113061722-B | Extraction method for separating calcium from low-temperature calcium-containing brine to extract lithium and application of extraction method | 湘潭大学 | 2022-08-09 | — | — | CN | disclosed |
| CN-111868842-B | Conductive paste with stable viscosity over time | 株式会社则武 | 2021-11-19 | — | — | CN | disclosed |
| CN-113061722-A | Extraction method for separating calcium from low-temperature calcium-containing brine to extract lithium and application of extraction method | 湘潭大学 | 2021-07-02 | — | — | CN | disclosed |
| CN-110669938-B | Extraction system for separating magnesium from magnesium-containing brine by using secondary amide/alkyl ketone composite solvent and extracting lithium, extraction method and application thereof | 湘潭大学 | 2021-04-13 | — | — | CN | disclosed |
| CN-110656249-B | Extraction system for separating magnesium from magnesium-containing brine by using secondary amide/alkane composite solvent, extraction method and application thereof | 湘潭大学 | 2021-03-23 | — | — | CN | disclosed |
| CN-111868842-A | Conductive paste with stable viscosity over time | 株式会社则武 | 2020-10-30 | — | — | CN | disclosed |
| CN-110669938-A | Extraction system for separating magnesium from magnesium-containing brine by using secondary amide/alkyl ketone composite solvent and extracting lithium, extraction method and application thereof | 湘潭大学 | 2020-01-10 | — | — | CN | disclosed |
| US-20110112199-A1 | PHARMACEUTICAL FOR ORAL DELIVERY COMPRISING MGBG AND METHODS OF TREATING DISEASE | PATHOLOGICA LLC (US) | 2011-05-12 | — | — | US | disclosed |
| US-7700771-B2 | Heterocyclic compound which may be used as a medicine having p38 MAP kinase inhibitory activity | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2010-04-20 | — | — | US | disclosed |
| US-20080200501-A1 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS S.A. (CH) | 2008-08-21 | — | — | US | disclosed |
| US-20080171753-A1 | Carbamoyl-Substituted Spiro Derivative | MSD K.K. (JP) | 2008-07-17 | — | — | US | disclosed |
| CN-101189002-A | Methods for modulating macrophage proliferation in ocular disease using polyamine analogs | PATHOLOGICA LLC (US) | 2008-05-28 | — | — | CN | disclosed |
| EP-1855663-A2 | METHODS FOR MODULATING MACROPHAGE PROLIFERATION IN OCULAR DISEASE USING POLYAMINE ANALOGS | Pathologica, LLC. (US) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006091522-A2 | METHODS FOR MODULATING MACROPHAGE PROLIFERATION IN OCULAR DISEASE USING POLYAMINE ANALOGS | PATHOLOGICA, LLC. (US) | 2006-08-31 | — | — | WO | disclosed |
| CN-1606694-A | Methods for monitoring and treating amyotrophic lateral sclerosis | SLIL BIOMEDICAL CORP (US) | 2005-04-13 | — | — | CN | disclosed |
| CN-1099388-A | Heteroatom-bearing ligands and metal complexes thereof | BRISTOL MYERS SQIBB COMPANY (US) | 1995-03-01 | — | — | CN | disclosed |
| US-4992150-A | Telomer with alpha-olefin;oil and fuel additive | NIPPON OIL CO, LTD. (JP) | 1991-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080171753-A1 | Carbamoyl-Substituted Spiro Derivative | HRH3, HRH4, HRH2 | TSHR 120/4885ALDH1A1 1954/4885EPHX1 907/4885 |
| US-20080200501-A1 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | CNR2, CNR1, OPRL1 | TSHR 1795/4885ALDH1A1 4441/4885EPHX1 1904/4885 |
| US-20110112199-A1 | PHARMACEUTICAL FOR ORAL DELIVERY COMPRISING MGBG AND METHODS OF TREATING DISEASE | BPGM, PYGB, EDNRB | TSHR 1498/4885ALDH1A1 1462/4885EPHX1 2908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.