Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.87 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.87 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.58 |
| ▸ | ADH1B | P00325 | 2/20 | 0.57 |
| ▸ | ADH1C | P00326 | 2/20 | 0.57 |
| ▸ | ADH1A | P07327 | 2/20 | 0.57 |
| ▸ | ADH7 | P40394 | 2/20 | 0.57 |
| ▸ | ADH4 | P08319 | 1/20 | 0.57 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.56 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.56 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.56 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.56 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5313856 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL5165020 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL4315670 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL8980568 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL8980623 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL6545006 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL25210211 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL5500928 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL21611676 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL237903 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120021055-A1 | NITRIC OXIDE-RELEASING PARTICLES FOR NITRIC OXIDE THERAPEUTICS AND BIOMEDICAL APPLICATIONS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2012-01-26 | — | — | US | disclosed |
| EP-1766183-A1 | ENHANCEMENT MODIFIERS FOR GAS HYDRATE INHIBITORS | Baker Hughes Incorporated (US) | 2007-03-28 | — | — | EP | disclosed |
| WO-2005116399-A1 | ENHANCEMENT MODIFIERS FOR GAS HYDRATE INHIBITORS | BAKER HUGHES INCORPORATED (US) | 2005-12-08 | — | — | WO | disclosed |
| US-5536425-A | DURABILITY | SONY CORPORATION (JP) | 1996-07-16 | — | — | US | disclosed |
| US-5453539-A | Durability | SONY CORPORATION (JP) | 1995-09-26 | — | — | US | disclosed |
| EP-0519406-A2 | Novel perfluoropolyether derivatives, and lubricants and magnetic recording medium using the same | SONY CORPORATION (JP) | 1992-12-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120021055-A1 | NITRIC OXIDE-RELEASING PARTICLES FOR NITRIC OXIDE THERAPEUTICS AND BIOMEDICAL APPLICATIONS | NOS2, NOS3, NOS1 | TSHR 673/4885ALDH1A1 1868/4885EPHX1 1648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.