Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 6/20 | 0.38 |
| ▸ | DRD3 | P35462 | 3/20 | 0.38 |
| ▸ | HRH1 | P35367 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5317298 | 0.94 | OPRM1 (0.41) | PPARGPPARAGRIN2DGRIN3BGRIN1 | |
| SCHEMBL3814747 | 0.78 | OPRM1 (0.45) | GRIN2DGRIN3BADRA1DADRA1AADRA1B | |
| SCHEMBL5315889 | 0.73 | POLB (0.56) | ADRA1AMEN1POLBKMT2AKCNH2 | |
| SCHEMBL19691780 | 0.72 | MEN1 (0.33) | MEN1POLBKMT2ASLC6A2SLC6A4 | |
| SCHEMBL14840627 | 0.70 | OPRM1 (0.43) | GRIN2DGRIN3BADRA1DADRA1AADRA1B | |
| SCHEMBL20147416 | 0.70 | OPRM1 (0.50) | GRIN2DGRIN3BADRA1DADRA1AADRA1B | |
| SCHEMBL654281 | 0.69 | CYP2D6 (0.49) | HTR1ASLC6A2HTR2ASLC6A4HTR7 | |
| SCHEMBL652763 | 0.69 | SLC6A2 (0.41) | KCNH2HTR1ASLC6A2SLC6A4 | |
| SCHEMBL27463353 | 0.69 | GRIN2D (0.48) | GRIN2DGRIN3BADRA1DADRA1AADRA1B | |
| SCHEMBL20147864 | 0.68 | OPRM1 (0.48) | GRIN2DGRIN3BADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007073432-A2 | PIPERIDINE DERIVATIVES AND METHODS OF USE | CHEMOCENTRYX, INC. (US) | 2007-06-28 | — | — | WO | disclosed |