Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | GPR183 | P32249 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CCR1 | P32246 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ATF4 | P18848 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14494792 | 0.94 | FKBP1A (0.60) | POLBHPGDMAPTRAB9AFKBP1A | |
| SCHEMBL5317162 | 0.87 | POLB (0.54) | POLBHPGDMAPTRAB9AFKBP1A | |
| SCHEMBL4634714 | 0.85 | POLB (0.52) | POLBHPGDMAPTRAB9AFKBP1A | |
| SCHEMBL5317276 | 0.82 | ALDH1A1 (0.60) | POLBHPGDMAPTRAB9AMEN1 | |
| SCHEMBL5059586 | 0.81 | CYP3A4 (0.69) | POLBHPGDMAPTRAB9AFKBP1A | |
| SCHEMBL5059273 | 0.81 | CYP3A4 (0.69) | POLBHPGDMAPTRAB9AFKBP1A | |
| SCHEMBL2471606 | 0.80 | MEN1 (0.54) | POLBHPGDMAPTRAB9AFKBP1A | |
| SCHEMBL4634497 | 0.79 | CCR1 (0.59) | HPGDMAPTTSHRCCR1LMNA | |
| SCHEMBL3063019 | 0.79 | HSD11B1 (0.45) | POLBMEN1KMT2AALDH1A1HTT | |
| SCHEMBL1730431 | 0.77 | FKBP1A (0.79) | POLBHPGDMAPTRAB9AFKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007073432-A2 | PIPERIDINE DERIVATIVES AND METHODS OF USE | CHEMOCENTRYX, INC. (US) | 2007-06-28 | — | — | WO | disclosed |
| WO-2007073432-A2 | PIPERIDINE DERIVATIVES AND METHODS OF USE | CHEMOCENTRYX, INC. (US) | 2007-06-28 | — | — | WO | disclosed |