Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 8/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | DRD2 | P14416 | 1/20 | 0.68 |
| ▸ | DRD4 | P21917 | 1/20 | 0.68 |
| ▸ | DRD3 | P35462 | 1/20 | 0.68 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.67 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.61 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.61 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.60 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.57 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.57 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5312136 | 0.91 | KMT2A (0.64) | LTA4HKMT2ADRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL1450124 | 0.88 | LTA4H (0.60) | LTA4HKMT2ADRD2DRD4DRD3 | |
| SCHEMBL3045089 | 0.87 | LTA4H (1.00) | LTA4H | |
| SCHEMBL5315667 | 0.86 | LTA4H (0.74) | LTA4HCHRM4 | |
| SCHEMBL5335853 | 0.86 | LTA4H (0.71) | LTA4HKMT2ACHRM4MCHR2MCHR1 | |
| SCHEMBL5333591 | 0.84 | LTA4H (0.71) | LTA4HCHRM4POLB | |
| Hydrochloric Acid SCHEMBL1448762 | 0.83 | KMT2A (0.65) | LTA4HKMT2ADRD2DRD4DRD3 | |
| SCHEMBL3036726 | 0.83 | LTA4H (0.76) | LTA4HKMT2ACHRM4 | |
| SCHEMBL3030359 | 0.83 | LTA4H (0.76) | LTA4HKMT2ACHRM4 | |
| SCHEMBL9078087 | 0.82 | DRD4 (1.00) | KMT2ADRD2DRD4DRD3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007079003-A2 | AMIDE INHIBITORS OF LEUKOTRIENE A4 HYDROLASE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-07-12 | — | — | WO | disclosed |
| US-20070155727-A1 | Amide inhibitors of leukotriene A4 hydrolase | SCHERING AKTIENGESSELLSCHAFT (DE) | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155727-A1 | Amide inhibitors of leukotriene A4 hydrolase | LTA4H, LTB4R, LTC4S | LTA4H 1/4885KMT2A 1929/4885DRD2 2126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.