Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 7/20 | 0.59 |
| ▸ | RAB9A | P51151 | 7/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 4/20 | 0.58 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1817366 | 0.81 | GRM5 (0.60) | KMT2AMEN1KDM4EMAPTGAA | |
| SCHEMBL4499177 | 0.80 | S1PR4 (0.51) | KMT2AMEN1KDM4EALDH1A1POLB | |
| SCHEMBL14573319 | 0.78 | CHRNA7 (0.70) | KMT2AMEN1CHRNA7 | |
| SCHEMBL10473593 | 0.77 | RAB9A (0.62) | KMT2AMEN1KDM4EALDH1A1NPC1 | |
| SCHEMBL485711 | 0.77 | MEN1 (0.82) | KMT2AMEN1KDM4EMAPTGAA | |
| SCHEMBL5315263 | 0.77 | CHRNA7 (0.69) | CHRNA7 | |
| SCHEMBL5315210 | 0.76 | CHRNA7 (0.61) | MEN1KDM4EALDH1A1CHRNA7 | |
| SCHEMBL28884580 | 0.75 | ALDH1A1 (0.64) | KMT2AMEN1KDM4EMAPTGAA | |
| SCHEMBL29934023 | 0.75 | ALDH1A1 (0.64) | KMT2AMEN1KDM4EMAPTGAA | |
| SCHEMBL1134467 | 0.75 | SMN1; SMN2 (0.67) | KDM4EGAAALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007062459-A1 | SELECTIVE KINASE INHIBITORS BASED ON PYRIDINE SCAFFOLD | CYTOPIA RESEARCH PTY LTD (AU) | 2007-06-07 | — | — | WO | disclosed |