Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 3/20 | 0.61 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.49 |
| ▸ | SCN10A | Q9Y5Y9 | 5/20 | 0.47 |
| ▸ | BLK | P51451 | 3/20 | 0.45 |
| ▸ | BTK | Q06187 | 2/20 | 0.45 |
| ▸ | CTSA | P10619 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5315263 | 0.89 | CHRNA7 (0.69) | CHRNA7S1PR4SCN10ACTSAKCNH2 | |
| SCHEMBL5315413 | 0.84 | CHRNA7 (0.57) | CHRNA7S1PR4SCN10ACTSASCN2A | |
| SCHEMBL14573319 | 0.82 | CHRNA7 (0.70) | CHRNA7S1PR4SCN10ACTSAKCNH2 | |
| SCHEMBL5313064 | 0.81 | CHRNA7 (0.66) | CHRNA7S1PR4SCN10ACTSAKCNH2 | |
| SCHEMBL5312509 | 0.81 | CHRNA7 (0.53) | CHRNA7S1PR4SCN10ACTSASCN2A | |
| SCHEMBL14494777 | 0.80 | CHRNA7 (0.55) | CHRNA7S1PR4SCN10ABTKCTSA | |
| SCHEMBL5317038 | 0.79 | BTK (0.57) | CHRNA7BTK | |
| SCHEMBL9789598 | 0.78 | ALDH1A1 (0.68) | S1PR4KDM4EALDH1A1MEN1 | |
| SCHEMBL14494779 | 0.78 | CHRNA7 (0.53) | CHRNA7S1PR4SCN10ACTSASCN2A | |
| SCHEMBL6436030 | 0.78 | CYP11B2 (0.58) | ALDH1A1CDK8MEN1PSIP1AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007062459-A1 | SELECTIVE KINASE INHIBITORS BASED ON PYRIDINE SCAFFOLD | CYTOPIA RESEARCH PTY LTD (AU) | 2007-06-07 | — | — | WO | disclosed |