Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | ACVR1 | Q04771 | 4/20 | 0.52 |
| ▸ | GRM4 | Q14833 | 5/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | COMT | P21964 | 1/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | TTK | P33981 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29492647 | 1.00 | NPC1 (0.55) | NPC1RAB9AMAPTACVR1GRM4 | |
| SCHEMBL23555407 | 0.98 | NPC1 (0.54) | NPC1RAB9AMAPTACVR1GRM4 | |
| SCHEMBL12386951 | 0.87 | CA12 (0.59) | NPC1RAB9AMAPTACVR1COMT | |
| SCHEMBL27430955 | 0.86 | ACVR1 (0.52) | NPC1RAB9AMAPTACVR1GRM4 | |
| SCHEMBL23555710 | 0.86 | CA12 (0.61) | NPC1RAB9AMAPTACVR1COMT | |
| SCHEMBL12074333 | 0.85 | PIK3CA (0.65) | NPC1RAB9AACVR1GRM4HTR2B | |
| SCHEMBL35327 | 0.84 | TGFBR1 (0.60) | NPC1RAB9AMAPTACVR1GRM4 | |
| SCHEMBL30439957 | 0.84 | TGFBR1 (0.60) | NPC1RAB9AMAPTACVR1GRM4 | |
| SCHEMBL28647092 | 0.84 | ACVR1 (0.51) | NPC1RAB9AMAPTACVR1GRM4 | |
| SCHEMBL28018853 | 0.82 | NPC1 (0.47) | NPC1RAB9AMAPTACVR1GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116466-B | Catalytic synthesis method of polysubstituted quinoline derivative | 浙江万里学院 | 2023-02-10 | — | — | CN | claimed |
| US-11770974-B2 | P active materials for organic photoelectric conversion layers in organic photodiodes | SONY CORPORATION (JP) | 2023-09-26 | — | — | US | disclosed |
| CN-114250479-B | Novel method for synthesizing alkyl-substituted nitrogen-containing heterocycle by cerium salt catalysis | 北京工业大学 | 2023-09-01 | — | — | CN | disclosed |
| CN-111116466-B | Catalytic synthesis method of polysubstituted quinoline derivative | 浙江万里学院 | 2023-02-10 | — | — | CN | disclosed |
| CN-114250479-A | Novel method for synthesizing alkyl-substituted nitrogen-containing heterocycle under catalysis of cerium salt | 北京工业大学 | 2022-03-29 | — | — | CN | disclosed |
| CN-113527198-A | Method for preparing 4-arylquinoline from 2-aminodiaryl methanol | 长沙资材科技有限公司 | 2021-10-22 | — | — | CN | disclosed |
| US-20210193935-A1 | P ACTIVE MATERIALS FOR ORGANIC PHOTOELECTRIC CONVERSION LAYERS IN ORGANIC PHOTODIODES | SONY CORPORATION (JP) | 2021-06-24 | — | — | US | disclosed |
| WO-2021082714-A1 | NITROGEN-CONTAINING COMPOUND, ELECTRONIC COMPONENT AND ELECTRONIC DEVICE | 陕西莱特光电材料股份有限公司 | 2021-05-06 | — | — | WO | disclosed |
| CN-111116466-A | Catalytic synthesis method of polysubstituted quinoline derivative | 浙江万里学院 | 2020-05-08 | — | — | CN | disclosed |
| US-20150376182-A1 | Substituted Acetylene Derivatives and their Use as Positive Allosteric Modulators of mGluR4 | MERCK PATENT GMBH (DE) | 2015-12-31 | — | — | US | disclosed |
| US-8735577-B2 | 1,3,5-triazine derivative, process for producing same, and organic electroluminescent element comprising same as constituent component | TOSOH CORPORATION (JP) | 2014-05-27 | — | — | US | disclosed |
| US-20110190494-A1 | 1,3,5-TRIAZINE DERIVATIVE, PROCESS FOR PRODUCING SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME AS CONSTITUENT COMPONENT | TOSOH CORPORATION (JP) | 2011-08-04 | — | — | US | disclosed |
| WO-2007074491-A1 | HETEROTRICYCLIC AMIDE DERIVATIVES AS NEUROKININ-l (NKl) RECEPTOR LIGANDS | UNIVERSITA DEGLI STUDI DI SIENA (IT) | 2007-07-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150376182-A1 | Substituted Acetylene Derivatives and their Use as Positive Allosteric Modulators of mGluR4 | GRM4, GRIA4, GRIK4 | NPC1 2651/4885RAB9A 2715/4885MAPT 1613/4885 |
| US-20110190494-A1 | 1,3,5-TRIAZINE DERIVATIVE, PROCESS FOR PRODUCING SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME AS CONSTITUENT COMPONENT | ASH2L, SETDB1, KAT5 | NPC1 4344/4885RAB9A 4644/4885MAPT 2757/4885 |
| US-11770974-B2 | P active materials for organic photoelectric conversion layers in organic photodiodes | JUP, L1CAM, EPCAM | NPC1 3239/4885RAB9A 2248/4885MAPT 1030/4885 |
| US-20210193935-A1 | P ACTIVE MATERIALS FOR ORGANIC PHOTOELECTRIC CONVERSION LAYERS IN ORGANIC PHOTODIODES | JUP, L1CAM, EPCAM | NPC1 3239/4885RAB9A 2248/4885MAPT 1030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.