Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.85 |
| ▸ | NPC1 | O15118 | 11/20 | 0.85 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.79 |
| ▸ | HTT | P42858 | 4/20 | 0.79 |
| ▸ | MAPT | P10636 | 8/20 | 0.72 |
| ▸ | LDHA | P00338 | 1/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30387733 | 0.88 | NPC1 (1.00) | RAB9ANPC1SMN1; SMN2HTTMAPT | |
| SCHEMBL5315708 | 0.87 | TRPV1 (0.82) | RAB9ANPC1SMN1; SMN2HTTMAPT | |
| SCHEMBL9679499 | 0.87 | NPC1 (0.79) | RAB9ANPC1SMN1; SMN2HTTMAPT | |
| SCHEMBL5316955 | 0.86 | RAB9A (0.86) | RAB9ANPC1SMN1; SMN2HTTMAPT | |
| SCHEMBL6979665 | 0.84 | NPC1 (0.72) | RAB9ANPC1SMN1; SMN2HTTMAPT | |
| SCHEMBL5316241 | 0.84 | MAPT (1.00) | RAB9ANPC1SMN1; SMN2HTTMAPT | |
| SCHEMBL5315753 | 0.84 | NPC1 (0.70) | RAB9ANPC1SMN1; SMN2HTTMAPT | |
| SCHEMBL5312716 | 0.84 | RAB9A (0.70) | RAB9ANPC1SMN1; SMN2HTTMAPT | |
| SCHEMBL3923955 | 0.83 | LDHA (1.00) | RAB9ANPC1SMN1; SMN2HTTMAPT | |
| SCHEMBL4664159 | 0.82 | LDHA (0.80) | RAB9ANPC1SMN1; SMN2HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007067757-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS FOR MODULATING TRPV1 | AMPHORA DISCOVERY CORPORATION (US) | 2007-06-14 | — | — | WO | claimed |
| WO-2007067757-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS FOR MODULATING TRPV1 | AMPHORA DISCOVERY CORPORATION (US) | 2007-06-14 | — | — | WO | disclosed |