Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.72 |
| ▸ | RAB9A | P51151 | 10/20 | 0.72 |
| ▸ | LDHA | P00338 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1261509 | 0.88 | NPC1 (0.75) | NPC1RAB9ALDHASMN1; SMN2RXFP1 | |
| SCHEMBL20481983 | 0.86 | NPC1 (0.78) | NPC1RAB9ALDHASMN1; SMN2HTT | |
| SCHEMBL14549421 | 0.85 | NPC1 (0.59) | NPC1RAB9ALDHASMN1; SMN2RXFP1 | |
| SCHEMBL8574737 | 0.85 | DYRK1A (0.62) | NPC1RAB9ALDHASMN1; SMN2RXFP1 | |
| SCHEMBL5314650 | 0.84 | RAB9A (0.85) | NPC1RAB9ALDHASMN1; SMN2RXFP1 | |
| SCHEMBL22208955 | 0.84 | TDP1 (0.68) | NPC1RAB9ALDHASMN1; SMN2RXFP1 | |
| SCHEMBL8566294 | 0.83 | RAB9A (0.68) | NPC1RAB9ALDHASMN1; SMN2RXFP1 | |
| SCHEMBL23409082 | 0.83 | NPC1 (0.52) | NPC1RAB9ALDHASMN1; SMN2RXFP1 | |
| SCHEMBL121976 | 0.83 | RAB9A (0.52) | NPC1RAB9ALDHASMN1; SMN2RXFP1 | |
| SCHEMBL18644551 | 0.83 | NPC1 (0.56) | NPC1RAB9ALDHASMN1; SMN2RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260125378-A2 | Heterocyclic Compounds | BEONE MEDICINES I GMBH (CH) | 2026-05-07 | — | — | US | disclosed |
| EP-4709725-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | Progentos Therapeutics, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| EP-4658656-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES | Beone Medicines I GmbH (CH) | 2025-12-10 | — | — | EP | disclosed |
| EP-4658650-A1 | HETEROCYCLIC COMPOUNDS | Beone Medicines I GmbH (CH) | 2025-12-10 | — | — | EP | disclosed |
| US-20250353846-A1 | Heterocyclic Compounds | BEONE MEDICINES I GMBH (CH) | 2025-11-20 | — | — | US | disclosed |
| US-20250346597-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES | BEONE MEDICINES I GMBH (CH) | 2025-11-13 | — | — | US | disclosed |
| WO-2024233642-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | PROGENTOS THERAPEUTICS, INC. (US) | 2024-11-14 | — | — | WO | disclosed |
| EP-4457224-A1 | HETEROCYCLIC COMPOUNDS | BeiGene Switzerland GmbH (CH) | 2024-11-06 | — | — | EP | disclosed |
| US-20240327417-A1 | HETEROCYCLIC COMPOUNDS | BEIGENE SWITZERLAND GMBH (CH) | 2024-10-03 | — | — | US | disclosed |
| WO-2024160277-A1 | HETEROCYCLIC COMPOUNDS | BEIGENE, LTD. (KY) | 2024-08-08 | — | — | WO | disclosed |
| EP-0606248-B1 | HETEROARYL AMINES AS NOVEL ACETYL CHOLINESTERASE INHIBITORS | EISAI CO LTD (JP) | 2003-03-26 | — | — | EP | disclosed |
| US-20020049210-A1 | Heteroaryl amines as novel acetylcholinesterase inhibitors | CHEN YUHPYNG L (US) | 2002-04-25 | — | — | US | disclosed |
| US-6303633-B1 | FOR THERAPY AND PROPHYLAXIS OF ALZHEIMER'S DISEASE | PFIZER INC | 2001-10-16 | — | — | US | disclosed |
| US-6124321-A | Heteroaryl amines as novel acetyl cholinesterase inhibitors | PFIZER INC (US) | 2000-09-26 | — | — | US | disclosed |
| US-5965574-A | Heteroaryl amines as novel acetylcholinesterase inhibitors | CHEN YUHPYNG LIANG (US) | 1999-10-12 | — | — | US | disclosed |
| CN-1035615-C | heteroaryl amines as acetylcholinesterase inhitibors | PFIZER (US) | 1997-08-13 | — | — | CN | disclosed |
| US-5574046-A | Heteroaryl amines as novel acetylcholinesterase inhibitors | PFIZER INC. (US) | 1996-11-12 | — | — | US | disclosed |
| EP-0606248-A1 | HETEROARYL AMINES AS NOVEL ACETYL CHOLINESTERASE INHIBITORS | Eisai Co., Ltd. (JP) | 1994-07-20 | — | — | EP | disclosed |
| CN-1071166-A | Aromatic heterocycle amine as new acetylcholinesterase depressant | PFIZER (US) | 1993-04-21 | — | — | CN | disclosed |
| WO-1993007140-A1 | HETEROARYL AMINES AS NOVEL ACETYL CHOLINESTERASE INHIBITORS | PFIZER INC. (US) | 1993-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260125378-A2 | Heterocyclic Compounds | NFATC1, CD4, MALT1 | NPC1 978/4885RAB9A 1314/4885LDHA 2597/4885 |
| US-20240327417-A1 | HETEROCYCLIC COMPOUNDS | NFATC1, CD4, ACIN1 | NPC1 1729/4885RAB9A 957/4885LDHA 1384/4885 |
| US-20250353846-A1 | Heterocyclic Compounds | NFATC1, CD4, ACIN1 | NPC1 1729/4885RAB9A 957/4885LDHA 1384/4885 |
| US-20020049210-A1 | Heteroaryl amines as novel acetylcholinesterase inhibitors | ACHE, BCHE, CHAT | NPC1 1310/4885RAB9A 416/4885LDHA 3112/4885 |
| US-20250346597-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES | DGKG, DGKA, DGKK | NPC1 1908/4885RAB9A 1548/4885LDHA 3695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.