Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.79 |
| ▸ | NPC1 | O15118 | 2/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.78 |
| ▸ | LMNA | P02545 | 1/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.78 |
| ▸ | MEN1 | O00255 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | TP53 | P04637 | 1/20 | 0.76 |
| ▸ | RAB9A | P51151 | 1/20 | 0.76 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.72 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.72 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.72 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.72 |
| ▸ | ME2 | P23368 | 1/20 | 0.72 |
| ▸ | ME1 | P48163 | 1/20 | 0.72 |
| ▸ | ME3 | Q16798 | 1/20 | 0.72 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.70 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.70 |
| ▸ | THRB | P10828 | 1/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192211 | 0.95 | ALDH1A1 (0.72) | ALDH1A1NPC1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL11147683 | 0.93 | ALDH1A1 (0.90) | ALDH1A1NPC1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL17616061 | 0.92 | ALDH1A1 (0.68) | ALDH1A1NPC1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL10474169 | 0.92 | LMNA (0.77) | ALDH1A1NPC1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL6795359 | 0.91 | ALDH1A1 (0.94) | ALDH1A1NPC1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL3839081 | 0.90 | MEN1 (0.74) | ALDH1A1NPC1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL8009141 | 0.90 | ALDH1A1 (0.69) | ALDH1A1NPC1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL8585760 | 0.89 | NPC1 (0.67) | ALDH1A1NPC1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL5536418 | 0.89 | ALDH1A1 (0.67) | ALDH1A1NPC1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL7511057 | 0.88 | ALDH1A1 (0.68) | ALDH1A1NPC1KDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874573-A | Compounds with chelation affinity and selectivity for first transition series elements: use in medical therapy | CONCAT, INC. (US) | 1999-02-23 | — | — | US | claimed |
| US-20220031870-A1 | METAL COMPLEXES AND FLUORINATION THEREOF | UNIVERSITY OF SOUTHAMPTON (GB) | 2022-02-03 | — | — | US | disclosed |
| US-20160082136-A1 | METAL COMPLEXES AND FLUORINATION THEREOF | UNIVERSITY OF SOUTHAMPTON (GB) | 2016-03-24 | — | — | US | disclosed |
| EP-1382332-A1 | Method for inhibiting bacterial or fungal growth using a polyamine derivative as complexing agent | Chelator LLC (US) | 2004-01-21 | — | — | EP | disclosed |
| US-6165996-A | Compounds with chelation affinity selectivity for first transition series elements: use in medical therapy and diagnosis | CONCAT, INC. (US) | 2000-12-26 | — | — | US | disclosed |
| EP-0955044-A2 | Method of inhibiting bacterial or fungal growth using a complexing agent | CONCAT LTD. (US) | 1999-11-10 | — | — | EP | disclosed |
| EP-0841951-A2 | COMPOUNDS WITH CHELATION AFFINITY AND SELECTIVITY FOR FIRST TRANSITION SERIES ELEMENTS, AND THEIR USE IN MEDICAL THERAPY AND DIAGNOSIS | CONCAT LTD. (US) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997001360-A2 | COMPOUNDS WITH CHELATION AFFINITY AND SELECTIVITY FOR FIRST TRANSITION SERIES ELEMENTS AND THEIR USE IN MEDICAL THERAPY AND DIAGNOSIS | CONCAT, LTD. (US) | 1997-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220031870-A1 | METAL COMPLEXES AND FLUORINATION THEREOF | FOS, FGB, FOSB | ALDH1A1 3176/4885NPC1 664/4885KDM4E 3099/4885 |
| US-20160082136-A1 | METAL COMPLEXES AND FLUORINATION THEREOF | FOS, FGB, FOSB | ALDH1A1 3309/4885NPC1 747/4885KDM4E 3216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.