Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.45 |
| ▸ | MTTP | P55157 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HPGDS | O60760 | 2/20 | 0.41 |
| ▸ | SCD | O00767 | 3/20 | 0.40 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5312220 | 0.88 | SCD (0.47) | HDAC6MAPK14SCD | |
| SCHEMBL5313199 | 0.86 | HPGDS (0.52) | HDAC6GABRA5MAPK14CYP2C9MAPK11 | |
| SCHEMBL5312928 | 0.77 | SCD (0.50) | HDAC6GABRA5MAPK14SCD | |
| SCHEMBL5312258 | 0.77 | SCD (0.47) | SCD | |
| SCHEMBL5307724 | 0.75 | USP30 (0.47) | HDAC6SCDHDAC1HDAC8 | |
| SCHEMBL1542860 | 0.73 | GABRA5 (0.59) | GABRA5MAPK14CYP2C9MAPK11HPGDS | |
| SCHEMBL2295558 | 0.72 | SCD (0.59) | GABRA5MAPK14CYP2C9SCD | |
| SCHEMBL5315075 | 0.71 | SCD (0.50) | HDAC6GABRA5MAPK14CYP2C9SCD | |
| SCHEMBL5310783 | 0.71 | SCD (0.46) | SCD | |
| SCHEMBL5313203 | 0.71 | CNR2 (0.53) | SCDLTC4S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044085-A2 | HETEROARYL COMPOUNDS AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2007-04-19 | — | — | WO | disclosed |