Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 5/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 3/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5312220 | 0.89 | SCD (0.47) | SCDMAPK14HDAC6GABRA1 | |
| SCHEMBL5339306 | 0.84 | SCD (0.41) | SCDGABRA1 | |
| SCHEMBL5307870 | 0.81 | ASPH (0.43) | SCD | |
| SCHEMBL5314711 | 0.77 | HDAC6 (0.47) | SCDMAPK14HDAC6GABRA5 | |
| SCHEMBL5315830 | 0.73 | ASPH (0.48) | — | |
| SCHEMBL5310783 | 0.72 | SCD (0.46) | SCDCNR2GABRA1 | |
| SCHEMBL5376686 | 0.71 | NPC1 (0.39) | SCD | |
| SCHEMBL5310095 | 0.69 | KCNMA1 (0.48) | — | |
| SCHEMBL5822569 | 0.69 | SCD (0.58) | SCD | |
| SCHEMBL5313123 | 0.68 | CNR1 (0.45) | SCDMAPK14CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044085-A2 | HETEROARYL COMPOUNDS AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2007-04-19 | — | — | WO | disclosed |