SCHEMBL5314713

SCHEMBL5314713

COCN(C(=O)NC(=O)c1c(F)cccc1F)c1ccc(SC(F)(F)C(F)(F)F)cc1F

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 3/20 0.34
RAB9A P51151 2/20 0.33
CYP1A2 P05177 2/20 0.32
POLB P06746 1/20 0.31
KMT2A Q03164 2/20 0.31
NPC1 O15118 1/20 0.31
MEN1 O00255 1/20 0.30
USP2 O75604 1/20 0.30
MAPT P10636 1/20 0.30
ALOX15 P16050 1/20 0.30
BDKRB1 P46663 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5312164 0.94 TRPA1 (0.33) TRPA1RAB9ACYP1A2POLBKMT2A
SCHEMBL5312106 0.92 TRPA1 (0.35) TRPA1RAB9ACYP1A2POLBKMT2A
SCHEMBL5314454 0.89 TRPA1 (0.33) TRPA1RAB9ACYP1A2POLBKMT2A
SCHEMBL5313896 0.88 TLR7 (0.36) RAB9APOLBNPC1MAPT
SCHEMBL5310925 0.87 MEN1 (0.37) TRPA1RAB9ACYP1A2POLBKMT2A
SCHEMBL5313998 0.87 RAB9A (0.36) TRPA1RAB9ACYP1A2POLBKMT2A
SCHEMBL5311213 0.86 RAB9A (0.35) TRPA1RAB9ACYP1A2POLBKMT2A
SCHEMBL5389734 0.86 TLR7 (0.39) RAB9APOLBNPC1MAPT
SCHEMBL5315704 0.85 RAB9A (0.35) TRPA1RAB9ACYP1A2POLBKMT2A
SCHEMBL5314175 0.84 ATM (0.40) TRPA1RAB9ACYP1A2POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007066496-A1 BENZOYLUREA COMPOUND AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-06-14 WO disclosed