Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | HRH2 | P25021 | 4/20 | 0.51 |
| ▸ | HRH1 | P35367 | 4/20 | 0.51 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5316918 | 0.95 | KCNA5 (0.54) | CD274KCNH2HRH2HRH1KCNA5 | |
| SCHEMBL5316019 | 0.91 | KCNH2 (0.54) | CD274KCNH2HRH2HRH1KCNA5 | |
| SCHEMBL4134193 | 0.89 | KCNH2 (0.53) | CD274KCNH2HRH2HRH1KCNA5 | |
| SCHEMBL5318392 | 0.87 | CD274 (0.58) | CD274KCNH2MKNK1MKNK2CCR3 | |
| SCHEMBL5317369 | 0.86 | KCNH2 (0.60) | CD274KCNH2HRH2HRH1PRKAA2 | |
| SCHEMBL5317499 | 0.85 | CD274 (0.56) | CD274KCNH2MKNK1MKNK2CCR3 | |
| SCHEMBL5318987 | 0.85 | CD274 (0.56) | CD274KCNH2MKNK1MKNK2CCR3 | |
| SCHEMBL5315942 | 0.85 | CD274 (0.56) | CD274KCNH2MKNK1MKNK2CCR3 | |
| SCHEMBL5316471 | 0.85 | CD274 (0.56) | CD274KCNH2PRKAA2MKNK1MKNK2 | |
| SCHEMBL4137801 | 0.84 | KCNH2 (0.59) | KCNH2HRH2HRH1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007069986-A1 | NEW OXABISPIDINE COMPOUNDS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2007-06-21 | — | — | WO | disclosed |