Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 6/20 | 0.53 |
| ▸ | CCR4 | P51679 | 2/20 | 0.48 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 7/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 7/20 | 0.46 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14529947 | 0.88 | HSD11B1 (0.53) | HSD11B1FKBP1AITGB1ITGA4ITGB7 | |
| SCHEMBL5332792 | 0.88 | HSD11B1 (0.53) | HSD11B1FKBP1AITGB1ITGA4ITGB7 | |
| SCHEMBL12640491 | 0.79 | HCRTR1 (0.57) | HSD11B1ITGB1ITGA4ITGB7HCRTR1 | |
| SCHEMBL14529605 | 0.78 | ITGB1 (0.53) | HSD11B1ITGB1ITGA4ITGB7 | |
| SCHEMBL14529964 | 0.76 | HSD11B1 (0.65) | HSD11B1ITGB1ITGA4ITGB7HCRTR1 | |
| SCHEMBL14529616 | 0.76 | HSD11B1 (0.65) | HSD11B1ITGB1ITGA4ITGB7HCRTR1 | |
| SCHEMBL5315701 | 0.76 | HSD11B1 (0.49) | HSD11B1ITGB1ITGA4ITGB7HCRTR1 | |
| SCHEMBL5452294 | 0.76 | GAA (0.48) | HSD11B1ITGB1ITGA4ITGB7HCRTR1 | |
| SCHEMBL5345940 | 0.76 | TSHR (0.62) | HSD11B1ITGB1ITGA4ITGB7HCRTR1 | |
| SCHEMBL5345936 | 0.76 | TSHR (0.62) | HSD11B1ITGB1ITGA4ITGB7HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007057768-A2 | SULFONYL DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2007-05-24 | — | — | WO | disclosed |