SCHEMBL5314872

SCHEMBL5314872

COc1ccccc1OC(=O)C1(C)CO1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA4 P22748 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.41
POLB P06746 1/20 0.41
ATM Q13315 1/20 0.41
KMT2A Q03164 2/20 0.40
HTT P42858 2/20 0.40
MAPT P10636 1/20 0.40
PRSS1 P07477 1/20 0.40
ACR P10323 1/20 0.40
BCHE P06276 1/20 0.40
MEN1 O00255 1/20 0.40
MTNR1A P48039 1/20 0.40
MTNR1B P49286 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6450358 0.80 PDK2 (0.40) ALDH1A1CA12CA1CA2CA4
SCHEMBL28735245 0.80 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2KMT2AMAPTBCHE
SCHEMBL6450356 0.80 PDK2 (0.40) ALDH1A1CA12CA1CA2CA4
SCHEMBL14967776 0.77 L3MBTL1 (0.59) ALDH1A1SMN1; SMN2POLBATMKMT2A
SCHEMBL21597978 0.77 POLB (0.40) ALDH1A1CA12CA1CA2CA4
SCHEMBL236191 0.74 CA12 (0.59) ALDH1A1CA12CA1CA2CA4
SCHEMBL29655351 0.74 CA12 (0.59) ALDH1A1CA12CA1CA2CA4
1,2-Dimethoxybenzene SCHEMBL27898360 0.73 CA1 (0.72) ALDH1A1CA12CA1CA2CA4
SCHEMBL30909436 0.72 CA1 (0.62) ALDH1A1CA12CA1CA2CA4
SCHEMBL8579858 0.72 CA1 (0.62) ALDH1A1CA12CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007073847-A1 NOVEL POLYPEPTIDE HAVING ESTERASE ACTIVITY AND RECOMBINANT ESTERASE AND USE THEREOF DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) 2007-07-05 WO disclosed