Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL217030 | 0.82 | LIPG (0.46) | LIPGCYP3A4CYP2D6CYP2C9TLR8 | |
| SCHEMBL2353493 | 0.81 | FFAR1 (0.50) | LIPGCYP3A4CYP2D6CYP2C9SMN1; SMN2 | |
| SCHEMBL23704288 | 0.79 | FFAR1 (0.46) | CYP3A4CYP2D6CYP2C9SMN1; SMN2CYP1A2 | |
| SCHEMBL668402 | 0.78 | LIPG (0.43) | LIPGCYP3A4CYP2D6CYP2C9SMN1; SMN2 | |
| SCHEMBL2119420 | 0.78 | CYP3A4 (0.44) | LIPGCYP3A4CYP2D6CYP2C9SMN1; SMN2 | |
| SCHEMBL1726412 | 0.78 | TSHR (0.45) | LIPGCYP3A4CYP2D6CYP2C9SMN1; SMN2 | |
| SCHEMBL10935201 | 0.78 | LIPG (0.43) | LIPGCYP3A4CYP2D6CYP2C9SMN1; SMN2 | |
| SCHEMBL28073277 | 0.78 | FFAR1 (0.50) | LIPGCYP3A4CYP2D6CYP2C9SMN1; SMN2 | |
| SCHEMBL9356039 | 0.77 | LIPG (0.50) | LIPGCYP3A4CYP2D6CYP2C9SMN1; SMN2 | |
| SCHEMBL5500837 | 0.76 | FFAR1 (0.46) | LIPGCYP3A4CYP2D6CYP2C9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007041166-A2 | HIGHLY OXYGEN PERMEABLE RIGID CONTACT LENSES FROM POLYACETYLENES | THE LAGADO CORPORATION (US) | 2007-04-12 | — | — | WO | disclosed |