Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
| ▸ | BACE1 | P56817 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | RECQL | P46063 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.55 |
| ▸ | DRD2 | P14416 | 3/20 | 0.55 |
| ▸ | DRD1 | P21728 | 3/20 | 0.55 |
| ▸ | DRD4 | P21917 | 3/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.55 |
| ▸ | DRD3 | P35462 | 3/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.55 |
| ▸ | THPO | P40225 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1960568 | 0.81 | PLA2G1B (0.59) | KDM4EMAPTALDH1A1GAAALOX5 | |
| SCHEMBL15220214 | 0.81 | PLA2G1B (0.59) | KDM4EMAPTALDH1A1GAAALOX5 | |
| SCHEMBL4968038 | 0.81 | PLA2G1B (0.59) | KDM4EMAPTALDH1A1GAAALOX5 | |
| SCHEMBL8713328 | 0.79 | ALOX15 (0.57) | KDM4EMAPTALDH1A1GAAALOX5 | |
| SCHEMBL11422131 | 0.79 | KDM4E (0.57) | KDM4EMAPTALDH1A1GAAALOX5 | |
| SCHEMBL6339564 | 0.79 | ALOX15 (0.57) | KDM4EMAPTALDH1A1GAAALOX5 | |
| SCHEMBL8779967 | 0.76 | PNMT (0.53) | MAPTALDH1A1ALOX15TP53TAAR1 | |
| SCHEMBL8779961 | 0.76 | PNMT (0.53) | MAPTALDH1A1ALOX15TP53TAAR1 | |
| SCHEMBL22082812 | 0.76 | ALOX15 (0.61) | KDM4EMAPTALDH1A1GAAALOX5 | |
| SCHEMBL5287328 | 0.75 | KDM4E (0.70) | KDM4EMAPTALDH1A1GAAALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018000098-A1 | TREATMENT OF INFLAMMATORY MYOPATHIES | CIPHER PHARMACEUTICALS INC. (CA) | 2018-01-04 | — | — | WO | disclosed |
| WO-2006108424-A9 | BETA-2 ADRENOCEPTOR AGONISTS FOR TREATING CONNECTIVE TISSUE DISEASES OF THE SKIN | ASTION DEV AS (DK) | 2007-08-09 | — | — | WO | disclosed |
| WO-2006108424-A2 | BETA-2 ADRENOCEPTOR AGONISTS FOR TREATING CONNECTIVE TISSUE DISEASES OF THE SKIN | ASTION PHARMA A/S (DK) | 2006-10-19 | — | — | WO | disclosed |