Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7331339 | 0.88 | MAOB (0.42) | MAOBAOC3MAOASOS1GRM2 | |
| SCHEMBL1547682 | 0.83 | MAOB (0.47) | MAOBAOC3MAOASOS1FFAR1 | |
| SCHEMBL95960 | 0.82 | GPR84 (0.50) | FFAR1PPARGPPARDHTR2ASLC6A4 | |
| SCHEMBL6483029 | 0.82 | MAPT (0.44) | MAOBSOS1GRM2HTR2ASLC6A4 | |
| SCHEMBL4856586 | 0.81 | MAOB (0.54) | MAOBAOC3SOS1 | |
| SCHEMBL5706897 | 0.79 | MAOB (0.45) | MAOBAOC3MAOASOS1GRM2 | |
| SCHEMBL21490294 | 0.79 | MAOB (0.49) | MAOBAOC3FFAR1PPARGSLC6A4 | |
| SCHEMBL4194831 | 0.79 | MAOB (0.45) | MAOBAOC3MAOASOS1GRM2 | |
| SCHEMBL2212307 | 0.79 | LTA4H (0.46) | MAOBAOC3MEN1KMT2A | |
| SCHEMBL31533510 | 0.79 | MAOB (0.45) | MAOBAOC3MAOASOS1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007069986-A1 | NEW OXABISPIDINE COMPOUNDS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2007-06-21 | — | — | WO | claimed |
| WO-2007069986-A1 | NEW OXABISPIDINE COMPOUNDS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2007-06-21 | — | — | WO | disclosed |