SCHEMBL4856586

SCHEMBL4856586

NCCOc1ccc(F)c(F)c1

nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.54
AOC3 Q16853 1/20 0.54
TAAR1 Q96RJ0 1/20 0.50
LTA4H P09960 2/20 0.48
PLA2G2A P14555 1/20 0.48
PDK2 Q15119 1/20 0.43
SOS1 Q07889 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
FGFR1 P11362 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14084030 0.89 MAOB (0.53) MAOBAOC3TAAR1LTA4HPLA2G2A
SCHEMBL22171125 0.83 TAAR1 (0.47) MAOBAOC3TAAR1LTA4HPLA2G2A
SCHEMBL18295348 0.83 TAAR1 (0.47) MAOBAOC3TAAR1LTA4HPLA2G2A
Hydrochloric Acid SCHEMBL21595684 0.82 MRGPRX4 (0.46) MAOBAOC3TAAR1LTA4HPLA2G2A
SCHEMBL3525094 0.82 GPR84 (0.51) TAAR1LTA4HPLA2G2APDK2
SCHEMBL21601187 0.82 CARM1 (0.45) MAOBAOC3TAAR1LTA4HPLA2G2A
SCHEMBL21490294 0.81 MAOB (0.49) MAOBAOC3PDK2SMN1; SMN2
SCHEMBL2212307 0.81 LTA4H (0.46) MAOBAOC3LTA4HPDK2
SCHEMBL5706897 0.81 MAOB (0.45) MAOBAOC3SOS1SMN1; SMN2
SCHEMBL4194831 0.81 MAOB (0.45) MAOBAOC3SOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250345785-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS BIO RAD LABORATORIES INC (US) 2025-11-13 US claimed
US-11896969-B2 Anionic exchange-hydrophobic mixed mode chromatography resins BIO-RAD LABORATORIES, INC. (US) 2024-02-13 US claimed
US-20250345785-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS BIO RAD LABORATORIES INC (US) 2025-11-13 US disclosed
US-12364978-B2 Anionic exchange-hydrophobic mixed mode chromatography resins BIO-RAD LABORATORIES, INC. (US) 2025-07-22 US disclosed
US-20240261775-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS BIO-RAD LABORATORIES, INC. 2024-08-08 US disclosed
US-11896969-B2 Anionic exchange-hydrophobic mixed mode chromatography resins BIO-RAD LABORATORIES, INC. (US) 2024-02-13 US disclosed
WO-2021046284-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS BIO-RAD LABORATORIES, INC. (US) 2021-03-11 WO disclosed
US-20210069692-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS BIO-RAD LABORATORIES, INC. 2021-03-11 US disclosed
US-20210069692-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS BIO-RAD LABORATORIES, INC. 2021-03-11 US disclosed
US-7462613-B2 Pyridazinone derivatives as pharmaceuticals and pharmaceutical compositions containing them SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2008-12-09 US disclosed
US-7309701-B2 Pyridazinone derivatives as pharmaceuticals and pharmaceutical compositions containing them SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2007-12-18 US disclosed
EP-1611121-B1 PYRIDAZINONE DERIVATIVES AS CDK2-INHIBITORS AVENTIS PHARMA SA (FR) 2007-08-08 EP disclosed
EP-1581505-B1 PYRIDAZINONE DERIVATIVES AS GSK-3BETA INHIBITORS SANOFI AVENTIS DEUTSCHLAND (DE) 2007-08-01 EP disclosed
US-20050026918-A1 Novel pyridazinone derivatives as pharmaceuticals and pharmaceutical compositions containing them SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2005-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250345785-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS ABCG2, SLC7A1, MSR1 MAOB 4518/4885AOC3 3425/4885TAAR1 2870/4885
US-12364978-B2 Anionic exchange-hydrophobic mixed mode chromatography resins ABCG2, SLC7A1, MSR1 MAOB 4518/4885AOC3 3425/4885TAAR1 2870/4885
US-20240261775-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS ABCG2, SLC7A1, MSR1 MAOB 4518/4885AOC3 3425/4885TAAR1 2870/4885
US-20210069692-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS ABCG2, SLC7A1, MSR1 MAOB 4518/4885AOC3 3425/4885TAAR1 2870/4885
US-20050026918-A1 Novel pyridazinone derivatives as pharmaceuticals and pharmaceutical compositions containing them C5, ADRA2C, ADRA1A MAOB 169/4885AOC3 629/4885TAAR1 350/4885
US-11896969-B2 Anionic exchange-hydrophobic mixed mode chromatography resins ABCG2, SLC7A1, MSR1 MAOB 4518/4885AOC3 3425/4885TAAR1 2870/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.