Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5315345 | 1.00 | HDAC11 (0.50) | HDAC11KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL13067865 | 0.90 | HDAC11 (0.49) | HDAC11KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL13310493 | 0.89 | HDAC2 (0.64) | HDAC11HDAC2HDAC1HDAC7HDAC8 | |
| SCHEMBL2878907 | 0.83 | RARB (0.60) | HDAC11KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL641032 | 0.81 | HTR2C (0.43) | ALDH1A1HSD17B10RARBKMT2AHTR2C | |
| SCHEMBL7967589 | 0.77 | KDM4E (0.77) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL7967595 | 0.77 | KDM4E (0.77) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL405795 | 0.77 | HDAC11 (0.80) | HDAC11KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL405796 | 0.77 | HDAC11 (0.80) | HDAC11KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL13310487 | 0.74 | RARA (0.49) | HDAC11RARBHDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071605-A1 | THE USE OF ST1898 FOR THE TREATMENT OF RESTENOSIS | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2007-06-28 | — | — | WO | disclosed |