Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.46 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.45 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17372408 | 0.87 | CA12 (0.50) | EPHX2CA12CA1CA2CA7 | |
| SCHEMBL7934897 | 0.83 | EPHX2 (0.52) | EPHX2CA12CA1CA2CA7 | |
| SCHEMBL15630672 | 0.83 | EPHX2 (0.52) | EPHX2CA12CA1CA2CA7 | |
| SCHEMBL19049390 | 0.83 | LOXL2 (0.56) | EPHX2CA12CA1CA2CA7 | |
| SCHEMBL8130378 | 0.82 | MEN1 (0.50) | EPHX2CA12CA1CA2CA7 | |
| SCHEMBL7879611 | 0.81 | MEN1 (0.66) | CA12CA1CA2MEN1KMT2A | |
| SCHEMBL1695664 | 0.80 | LOXL2 (0.57) | EPHX2CA12CA1CA2CA7 | |
| SCHEMBL6444359 | 0.80 | LOXL2 (0.57) | EPHX2CA12CA1CA2CA7 | |
| SCHEMBL19002484 | 0.80 | CYP3A4 (0.56) | EPHX2CA12CA1CA2CA7 | |
| SCHEMBL9798143 | 0.80 | ALDH1A1 (0.58) | EPHX2MEN1KMT2ATPSAB1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592356-B2 | Triazoles as farnesyl transferase inhibitors | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-09-22 | — | — | US | disclosed |
| US-7592356-B2 | Triazoles as farnesyl transferase inhibitors | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-09-22 | — | — | US | disclosed |
| US-7511061-B2 | Triazoles as farnesyl transferase inhibitors | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-03-31 | — | — | US | disclosed |
| US-7511061-B2 | Triazoles as farnesyl transferase inhibitors | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-03-31 | — | — | US | disclosed |
| US-20080103150-A1 | Triazoles as Farnesyl Transferase Inhibitors | SAHA ASHIS K | 2008-05-01 | — | — | US | disclosed |
| US-20080103150-A1 | Triazoles as Farnesyl Transferase Inhibitors | SAHA ASHIS K | 2008-05-01 | — | — | US | disclosed |
| WO-2007069986-A1 | NEW OXABISPIDINE COMPOUNDS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2007-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080103150-A1 | Triazoles as Farnesyl Transferase Inhibitors | CYP7A1, HSD3B1, CES1 | EPHX2 352/4885CA12 4459/4885CA1 2415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.