Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23122581 | 0.76 | CCNB2 (0.43) | ALDH1A1MAP2K1ALOX15HTTRIPK1 | |
| SCHEMBL9171113 | 0.75 | KMT2A (0.51) | ALDH1A1HTTLMNAKDM4EGAA | |
| SCHEMBL523396 | 0.75 | PIN1 (0.42) | DAOALDH1A1CDK9DYRK1ADYRK1B | |
| SCHEMBL4362602 | 0.73 | KDM4C (0.50) | ALDH1A1RIPK1KDM4ENPSR1TP53 | |
| Hydrochloric Acid SCHEMBL2816871 | 0.73 | PIN1 (0.41) | DAOALDH1A1CDK9DYRK1ADYRK1B | |
| SCHEMBL3368051 | 0.71 | MAP2K1 (0.48) | ALDH1A1MAP2K1ALOX15HTTLMNA | |
| SCHEMBL15566492 | 0.71 | DAO (0.51) | DAORIPK1 | |
| SCHEMBL4333657 | 0.70 | RIPK1 (0.46) | DAOALDH1A1RIPK1FGFR1FLT1 | |
| SCHEMBL1699249 | 0.70 | ALDH1A1 (0.41) | DAOALDH1A1CDK9DYRK1ADYRK1B | |
| SCHEMBL29573599 | 0.70 | ALDH1A1 (0.41) | DAOALDH1A1CDK9DYRK1ADYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771448-A1 | AZAINDOLE CARBOXAMIDES | SCHWARZ PHARMA AG (DE) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006050976-A1 | AZAINDOLE CARBOXAMIDES | SCHWARZ PHARMA AG (DE) | 2006-05-18 | — | — | WO | disclosed |