Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5314621 | 0.85 | — | — | |
| SCHEMBL5314239 | 0.81 | — | — | |
| SCHEMBL3296616 | 0.80 | ALDH1A1 (0.38) | ALDH1A1LMNAHSD17B10ALOX15 | |
| SCHEMBL5313465 | 0.79 | ALDH1A1 (0.43) | ALDH1A1LMNA | |
| SCHEMBL5316397 | 0.79 | — | — | |
| SCHEMBL5316351 | 0.78 | — | — | |
| SCHEMBL3782478 | 0.76 | ALDH1A1 (0.47) | ALDH1A1LMNAHSD17B10ALOX15 | |
| SCHEMBL21054350 | 0.73 | ALDH1A1 (0.32) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL5315425 | 0.73 | TSHR (0.32) | — | |
| SCHEMBL5318085 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1471069-B1 | Preparation of silyl ketene acetals and disilyl ketene acetals | SHINETSU CHEMICAL CO (JP) | 2007-04-18 | — | — | EP | disclosed |
| US-7112710-B2 | Preparation of silyl ketene acetal and disilyl ketene acetal | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2006-09-26 | — | — | US | disclosed |
| US-20050256329-A1 | Preparation of silyl ketene acetal and disilyl ketene acetal | KIYOMORI AYUMU | 2005-11-17 | — | — | US | disclosed |
| US-6960679-B2 | Preparation of silyl ketene acetal and disilyl ketene acetal | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2005-11-01 | — | — | US | disclosed |
| US-20040215033-A1 | Preparation of silyl ketene acetal and disilyl ketene acetal | SHIN-ETSU CHEMICAL CO. LTD. (JP) | 2004-10-28 | — | — | US | disclosed |
| EP-1471069-A1 | Preparation of silyl ketene acetals and disilyl ketene acetals | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2004-10-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256329-A1 | Preparation of silyl ketene acetal and disilyl ketene acetal | TREH, DEGS1, PHYKPL | ALDH1A1 678/4885LMNA 931/4885HSD17B10 531/4885 |
| US-20040215033-A1 | Preparation of silyl ketene acetal and disilyl ketene acetal | TREH, PHYKPL, KAT8 | ALDH1A1 824/4885LMNA 1736/4885HSD17B10 414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.