Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 6/20 | 0.37 |
| ▸ | ACACA | Q13085 | 3/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4134708 | 0.94 | DRD2 (0.43) | DRD2HTR2CACACBACACACNR1 | |
| SCHEMBL4134705 | 0.94 | DRD2 (0.43) | DRD2HTR2CACACBACACACNR1 | |
| SCHEMBL5315744 | 0.88 | HTR2C (0.42) | DRD2HTR2CHTR2AHTR2BACACB | |
| SCHEMBL4126434 | 0.87 | HTR2A (0.51) | DRD2HTR2CHTR2AHTR2BACACB | |
| SCHEMBL4126436 | 0.87 | HTR2A (0.51) | DRD2HTR2CHTR2AHTR2BACACB | |
| SCHEMBL5315275 | 0.87 | HTR2C (0.50) | DRD2HTR2CHTR2AHTR2BACACB | |
| SCHEMBL5315320 | 0.83 | HTR2C (0.50) | HTR2CHTR2AHTR2BACACBACACA | |
| SCHEMBL4129039 | 0.81 | HTR2C (0.46) | DRD2HTR2CHTR2AHTR2BACACB | |
| SCHEMBL4129040 | 0.81 | HTR2C (0.46) | DRD2HTR2CHTR2AHTR2BACACB | |
| SCHEMBL4129089 | 0.81 | HTR2C (0.56) | DRD2HTR2CHTR2AHTR2BACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025144-A1 | 5-HT2C RECEPTOR AGONISTS AS ANORECTIC AGENTS | UNIVERSITY OF ILLINOIS - CHICAGO (US) | 2007-03-01 | — | — | WO | disclosed |