Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 1.00 |
| ▸ | HPGD | P15428 | 4/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | FPR1 | P21462 | 8/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2541804 | 0.80 | RAB9A (0.74) | KDM4EHPGDHSD17B10NPSR1TSHR | |
| SCHEMBL13904566 | 0.74 | ALDH1A1 (0.63) | KDM4EHPGDHSD17B10NPSR1TSHR | |
| SCHEMBL12722313 | 0.70 | ALDH1A1 (0.67) | KDM4EHPGDHSD17B10NPSR1TSHR | |
| SCHEMBL13904793 | 0.69 | ALDH1A1 (0.54) | KDM4EHPGDHSD17B10NPSR1TSHR | |
| SCHEMBL5274407 | 0.69 | ALDH1A1 (0.58) | KDM4EHPGDHSD17B10NPSR1TSHR | |
| SCHEMBL2545819 | 0.68 | SMN1; SMN2 (0.68) | KDM4EHPGDHSD17B10NPSR1TSHR | |
| SCHEMBL12238010 | 0.66 | NPC1 (0.77) | KDM4EHPGDHSD17B10NPSR1TSHR | |
| SCHEMBL5267160 | 0.65 | ALDH1A1 (0.60) | KDM4EHPGDHSD17B10NPSR1TSHR | |
| SCHEMBL4057641 | 0.65 | MAPT (0.66) | KDM4EHPGDHSD17B10NPSR1TSHR | |
| SCHEMBL5267169 | 0.64 | ALDH1A1 (0.73) | KDM4EHPGDHSD17B10NPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | claimed |
| WO-2007047579-A2 | A NOVEL THERAPEUTIC TARGET FOR PROTOZOAL DISEASES | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2007-04-26 | — | — | WO | claimed |
| WO-2007045096-A1 | OLIGOHETEROAROMATIC LUMINISCENT ASSEMBLIES AS HIGH-AFFINITY DNA SEQUENCE-DIRECTED LIGANDS | UNIVERSITY OF SASKATCHEWAN (CA) | 2007-04-26 | — | — | WO | disclosed |