SCHEMBL5315560

SCHEMBL5315560

NS(=O)(=O)C1COc2ccccc21

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA2 P00918 7/20 0.47
LTB4R Q15722 1/20 0.39
LTB4R2 Q9NPC1 1/20 0.39
PIK3CA P42336 2/20 0.39
AKT1 P31749 1/20 0.39
MTOR P42345 1/20 0.39
CYP19A1 P11511 1/20 0.38
TRPM8 Q7Z2W7 1/20 0.37
DRD2 P14416 1/20 0.36
DRD3 P35462 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CYP2D6 P10635 2/20 0.36
SLC6A2 P23975 2/20 0.36
SLC6A4 P31645 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22118298 0.84 PIK3CA (0.41) CA2PIK3CAAKT1MTORSMN1; SMN2
SCHEMBL22118297 0.84 PIK3CA (0.41) CA2PIK3CAAKT1MTORSMN1; SMN2
SCHEMBL6992306 0.73 HTR6 (0.39) CA2DRD2
SCHEMBL5864109 0.72 CA2 (0.54) CA2DRD3SLC6A2
SCHEMBL507362 0.71 LTB4R (0.43) CA2LTB4RLTB4R2CYP19A1TRPM8
SCHEMBL30888065 0.71 LTB4R (0.43) CA2LTB4RLTB4R2CYP19A1TRPM8
SCHEMBL5541762 0.71 LTB4R (0.47) LTB4RLTB4R2CYP19A1TRPM8DRD2
SCHEMBL29920552 0.71 CA2 (0.42) CA2LTB4RLTB4R2DRD2DRD3
SCHEMBL29920570 0.71 CA2 (0.42) CA2LTB4RLTB4R2DRD2DRD3
Hydrochloric Acid SCHEMBL1163031 0.69 LTB4R (0.42) CA2LTB4RLTB4R2CYP19A1TRPM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007052831-A1 PREVENTIVES/REMEDIES FOR URINARY DISTURBANCE TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-05-10 WO disclosed
CN-1589153-A Prevention or treatment of urinary disorders TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2005-03-02 CN disclosed