Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5315539 | 0.82 | CYP19A1 (0.44) | LMNA | |
| SCHEMBL5317681 | 0.79 | NPC1 (0.41) | MAPTSMN1; SMN2KMT2ANPC1L3MBTL1 | |
| SCHEMBL28161590 | 0.74 | CYP2D6 (0.50) | MAPTLMNASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL5312191 | 0.72 | CYP1A2 (0.40) | MAPTLMNASMN1; SMN2CYP1A2KMT2A | |
| SCHEMBL11510858 | 0.71 | LMNA (0.54) | MAPTLMNASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL1871973 | 0.70 | HSD17B10 (0.53) | MAPTLMNASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL5315937 | 0.69 | LMNA (0.41) | MAPTLMNASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL27734197 | 0.68 | CYP2D6 (0.54) | MAPTLMNASMN1; SMN2CYP1A2CYP2C19 | |
| Ethyl Isonicotinate SCHEMBL24935 | 0.67 | CA12 (0.62) | MAPTLMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL17797918 | 0.67 | ELANE (0.49) | MAPTCYP1A2CYP2C19KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1840158-A1 | METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE | Bridgestone Corporation (JP) | 2007-10-03 | — | — | EP | disclosed |