Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5315540 | 0.81 | CYP19A1 (0.45) | SMN1; SMN2KDM4E | |
| SCHEMBL5317685 | 0.78 | PKM (0.43) | LMNASMN1; SMN2KDM4ENPC1L3MBTL1 | |
| SCHEMBL14919008 | 0.75 | TSHR (0.55) | LMNACYP1A2CYP2C19CYP2C9SMN1; SMN2 | |
| SCHEMBL3910178 | 0.73 | KDM4E (0.43) | LMNACYP1A2CYP2C19CYP2C9SMN1; SMN2 | |
| SCHEMBL3908799 | 0.72 | KMT2A (0.44) | LMNACYP1A2CYP2C19CYP2C9SMN1; SMN2 | |
| SCHEMBL17641405 | 0.71 | KDM4E (0.57) | LMNAHSD17B10KDM4EKMT2AADRB2 | |
| SCHEMBL5310369 | 0.70 | ALDH1A1 (0.42) | CYP1A2CYP2C19SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL3914955 | 0.70 | CYP3A4 (0.45) | LMNACYP1A2CYP2C19CYP2C9SMN1; SMN2 | |
| SCHEMBL14501101 | 0.70 | ALDH1A1 (0.56) | LMNASMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL5315935 | 0.69 | MAPT (0.40) | LMNACYP1A2CYP2C19CYP2C9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1840158-A1 | METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE | Bridgestone Corporation (JP) | 2007-10-03 | — | — | EP | disclosed |