Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3227432 | 0.88 | KDM4E (0.71) | KDM4EALDH1A1MAPTKMT2AHSD17B10 | |
| SCHEMBL3227136 | 0.87 | MAPT (0.72) | KDM4EALDH1A1MAPTKMT2AHSD17B10 | |
| SCHEMBL4874531 | 0.79 | KDM4E (0.60) | KDM4EALDH1A1MAPTKMT2AHSD17B10 | |
| SCHEMBL30782359 | 0.78 | KDM4E (0.63) | KDM4EALDH1A1MAPTKMT2AHSD17B10 | |
| SCHEMBL2225084 | 0.78 | KDM4E (0.63) | KDM4EALDH1A1MAPTKMT2AHSD17B10 | |
| SCHEMBL4109638 | 0.76 | L3MBTL1 (0.57) | KDM4EALDH1A1MAPTKMT2AHSD17B10 | |
| SCHEMBL10746252 | 0.75 | ALDH1A1 (0.56) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL4736378 | 0.75 | KDM4E (0.53) | KDM4EALDH1A1MAPTHSD17B10GAA | |
| SCHEMBL2227187 | 0.75 | GAA (0.69) | KDM4EALDH1A1KMT2AHSD17B10GAA | |
| SCHEMBL5592386 | 0.75 | P2RY12 (0.63) | KDM4EP2RY12CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836189-A1 | NOVEL PYRIDINE COMPOUNDS | AstraZeneca AB (SE) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006073361-A1 | NOVEL PYRIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2006-07-13 | — | — | WO | disclosed |