Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.34 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5316114 | 0.89 | KMT2A (0.35) | TLR7RXFP1TLR8KCNK2MAPT | |
| SCHEMBL5316112 | 0.86 | POLB (0.39) | POLBMAPTLMNAMEN1USP2 | |
| SCHEMBL5314661 | 0.84 | ALDH1A1 (0.42) | TLR7TLR8MAPTLMNANPSR1 | |
| SCHEMBL5335591 | 0.83 | HTT (0.34) | POLBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5313311 | 0.83 | PDE4B (0.37) | KCNK2MAPTLMNAMEN1KMT2A | |
| SCHEMBL4149970 | 0.83 | RXFP1 (0.35) | POLBRXFP1KCNK2KCNK10DHODH | |
| SCHEMBL5316805 | 0.82 | MEN1 (0.34) | POLBMAPTMEN1USP2ALOX15 | |
| SCHEMBL5314189 | 0.82 | TLR7 (0.37) | POLBTLR7TLR8MAPTLMNA | |
| SCHEMBL5316854 | 0.82 | TLR7 (0.37) | POLBTLR7TLR8MAPTLMNA | |
| SCHEMBL5314296 | 0.82 | ALDH1A1 (0.35) | POLBLMNAKMT2AALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007066496-A1 | BENZOYLUREA COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-14 | — | — | WO | disclosed |