Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.60 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.53 |
| ▸ | CHRM3 known ✓ | P20309 | 2/20 | 0.53 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | BLM | P54132 | 1/20 | 0.70 |
| ▸ | DGKA | P23743 | 1/20 | 0.68 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.67 |
| ▸ | RAD52 | P43351 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.56 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.53 |
| ▸ | FABP3 | P05413 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.52 |
| ▸ | PAM | P19021 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.51 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5316384 | 0.98 | DGKA (0.71) | MAPTBLMDGKAADRA2AADRA1A | |
| Hydrochloric Acid SCHEMBL1517489 | 0.98 | DGKA (0.71) | MAPTBLMDGKAADRA2AADRA1A | |
| Hydrochloric Acid SCHEMBL5318921 | 0.98 | DGKA (0.71) | MAPTBLMDGKAADRA2AADRA1A | |
| Hydrochloric Acid SCHEMBL5266793 | 0.98 | DGKA (0.71) | MAPTBLMDGKAADRA2AADRA1A | |
| Hydrochloric Acid SCHEMBL5317635 | 0.98 | DGKA (0.71) | MAPTBLMDGKAADRA2AADRA1A | |
| SCHEMBL292302 | 0.98 | DGKA (0.70) | MAPTBLMDGKAADRA2AADRA1A | |
| Water SCHEMBL16968729 | 0.96 | DGKA (0.69) | MAPTBLMDGKAADRA2AADRA1A | |
| SCHEMBL200400 | 0.96 | DGKA (0.74) | MAPTBLMDGKAADRA2AADRA1A | |
| SCHEMBL8385098 | 0.96 | DGKA (0.74) | MAPTBLMDGKAADRA2AADRA1A | |
| SCHEMBL8385120 | 0.96 | DGKA (0.74) | MAPTBLMDGKAADRA2AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007079252-A2 | SUSTAINED RELEASE PHARMACEUTICAL COMPOSITIONS | AMPHASTAR PHARMACEUTICALS, INC. (US) | 2007-07-12 | — | — | WO | disclosed |
| US-20070154546-A1 | Sustained release pharmaceutical compositions | INTERNATIONAL MEDICATION SYSTEMS, LIMITED | 2007-07-05 | — | — | US | disclosed |
| US-4289831-A | QUATERNARY AMMONIUM SALT ANTISTATIC LAYER, MODULUS IMPROVER | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-09-15 | — | — | US | disclosed |
| EP-0004151-B1 | ANTISTATIC FILMS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-05-27 | — | — | EP | disclosed |
| US-4268583-A | PACKAGING MATERIALS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-05-19 | — | — | US | disclosed |
| US-4241144-A | POLYOXYALKYLENE AMINE SULFATE VOLATILE CASTING VEHICLE AND A QUATERNARY AMMONIUM PROVIDES ANTISTATICS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-12-23 | — | — | US | disclosed |
| EP-0004151-A1 | Antistatic films | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1979-09-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070154546-A1 | Sustained release pharmaceutical compositions | PLA2G2C, PLTP, F12 | ACHE 1591/4885CHRM1 839/4885CHRM3 1316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.